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CD303 rabbit pAb

CAT: 0855-ES8681-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8681-02Size:100 µL
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Background
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Description
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
UniProt
Q8WTT0
Swiss Prot
Q8WTT0
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic peptide from human protein at AA range: 91-140
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type II membrane protein .
Other Product Names
C-type lectin domain family 4 member C (Blood dendritic cell antigen 2; BDCA-2; C-type lectin superfamily member 7; Dendritic lectin; CD antigen CD303)
Gene ID (Human)
170482

UniProtKB · Q8WTT0

C-type lectin domain family 4 member C

CLC4C_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8WTT0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CLEC4C
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
D3DUU3, Q3T1C3, Q6UXS8, Q8WXX8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityImmunityInnate immunity

Coding sequence diversity

Alternative splicing

Ligand

CalciumLectinMetal-binding

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Domain

Signal-anchorTransmembraneTransmembrane helix