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DCT rabbit pAb

CAT: 0855-ES8595-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8595-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate., cofactor:Binds 2 zinc ions per subunit., function:Involved in regulating eumelanin and phaeomelanin levels., pathway:Pigment biosynthesis; melanin biosynthesis., similarity:Belongs to the tyrosinase family., subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.
Description
Catalytic activity: L-dopachrome = 5, 6-dihydroxyindole-2-carboxylate. Cofactor: Binds 2 zinc ions per subunit. function: Involved in regulating eumelanin and phaeomelanin levels. pathway: Pigment biosynthesis; melanin biosynthesis. similarity: Belongs to the tyrosinase family. subunit: Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex.
UniProt
P40126
Swiss Prot
P40126
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic peptide from human protein at AA range: 232-304
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, IHC-p 1:500-200, ELISA 1:10000-20000
Molecular Weight
59kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
59kD
Fragment
IgG
Subcellular Location
Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. .
Other Product Names
L-dopachrome tautomerase (DCT; DT; EC 5.3.3.12; L-dopachrome Delta-isomerase; Tyrosinase-related protein 2; TRP-2; TRP2)
Gene ID (Human)
1638

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