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FBXO7 rabbit pAb

CAT: 0855-ES8543-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8543-01Size:50 µL
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Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined. [provided by RefSeq, Jul 2008]
Description
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined. [provided by RefSeq, Jul 2008],
Product Name Alternative
FBXO7 FBX7
UniProt
Q9Y3I1
Swiss Prot
Q9Y3I1
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic peptide from human protein at AA range: 371-420
Target
FBXO7
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Buffer
-20°C/1 year
Molecular Weight
58kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
58kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Mitochondrion . Cytoplasm, cytosol . Predominantly cytoplasmic (PubMed:16096642) . A minor proportion is detected in the nucleus (PubMed:16096642) . Relocates from the cytosol to depolarized mitochondria (PubMed:23933751) . .
Other Product Names
FBXO7 FBX7
Gene ID (Human)
25793

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