Frizzled-4 rabbit pAb

• Background:

  Frizzled class receptor 4 (FZD4) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]

• Description:

  Frizzled class receptor 4 (FZD4) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008],

• UniProt:

  Q9ULV1

• Swiss Prot:

  Q9ULV1

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human FZD4. AA range:131-180

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

• Storage Conditions:

  -20°C/1 year

• Fragment:

  IgG

• Subcellular Location:

  Cell membrane ; Multi-pass membrane protein .

• Other Product Names:

  FZD4; Frizzled-4; Fz-4; hFz4; FzE4; CD antigen CD344

• Gene ID (Human):

  8322