Frizzled-9 rabbit pAb

• Background:

  Frizzled class receptor 9 (FZD9) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008]

• Description:

  Frizzled class receptor 9 (FZD9) Homo sapiens Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney. [provided by RefSeq, Jul 2008],

• Synonyms:

  FZD9; FZD3; Frizzled-9; Fz-9; hFz9; FzE6; CD antigen CD349

• Gene ID:

  8326

• UniProt:

  O00144

• Cellular Locus:

  Cell membrane ; Multi-pass membrane protein. Relocalizes DVL1 to the cell membrane leading to phosphorylation of DVL1 and AXIN1 relocalization to the cell membrane..

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Monkey

• Reactivity:

  Human; Mouse; Monkey

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human FZD9. AA range:542-591

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IF, ELISA

• Validated Applications:

  WB, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  64kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  64 kD

• Subcellular Location:

  Cell membrane ; Multi-pass membrane protein . Relocalizes DVL1 to the cell membrane leading to phosphorylation of DVL1 and AXIN1 relocalization to the cell membrane. .

• Other Product Names:

  FZD9; FZD3; Frizzled-9; Fz-9; hFz9; FzE6; CD antigen CD349

• Gene ID (Human):

  8326

• SwissProt (Human):

  O00144