Products for Research Use Only
RegisterLogin

CD141 rabbit pAb

CAT: 0855-ES7386-02Size: 100 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES7386-02Size:100 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia. [provided by RefSeq, Jul 2008],
Product Name Alternative
THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141
UniProt
P07204
Swiss Prot
P07204
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human THBD. AA range:526-575
Target
CD141
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
60kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
60kD
Fragment
IgG
Subcellular Location
Membrane; Single-pass type I membrane protein.
Other Product Names
THBD; THRM; Thrombomodulin; TM; Fetomodulin; CD antigen CD141
Gene ID (Human)
7056

UniProtKB · P07204

Thrombomodulin

TRBM_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P07204
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
THBD
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
TM
EC number
—
Processing
Precursor
Secondary accessions
Q8IV29, Q9UC32
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

Blood coagulationHemostasis

Disease

Disease variantHemolytic uremic syndromeThrombophilia

PTM

Disulfide bondGlycoproteinHydroxylationProteoglycan

Domain

EGF-like domainRepeatSignalTransmembraneTransmembrane helix

Cellular component

Membrane

Molecular function

Receptor

Related Products

CatalogName
ES4130-01CD148 rabbit pAb
ES4006-01CD161 rabbit pAb
ES8683-01CD151 rabbit pAb
ES4330-01CD101 rabbit pAb
ES20411-01CD14 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20659-01NBR1 Rabbit rabbit pAb
ES20825-01ATG7 Rabbit rabbit pAb
ES20831-01ATG13 Rabbit rabbit pAb
ES20599-01VEGF Rabbit rabbit pAb

Alternative Products

CatalogName
MBS9147856-01CD141/Thrombomodulin Rabbit PolymAb
APRab08210-01CD141 Rabbit Polyclonal Antibody
RDSA66285Thrombomodulin / CD141 Rabbit mAb
A22989PM-01CD141/Thrombomodulin Rabbit PolymAb®
A4155-01CD141/Thrombomodulin Rabbit pAb
GTR18702889-01CD141 Rabbit Monoclonal Antibody
MBS9469278-01Thrombomodulin/CD141 Rabbit mAb
A21238-01CD141/Thrombomodulin Rabbit mAb
GTR18798202-01CD141 Recombinant Rabbit mAb
GTR18052714-01CD141 rabbit pAb Antibody

Popular Products