SNAI 1 (phospho Ser246) rabbit pAb
CAT:
855-ES7245-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SNAI 1 (phospho Ser246) rabbit pAb
- Description: Snail family transcriptional repressor 1 (SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008],
- Synonyms: SNAI1; SNAH; Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna
- Gene ID: 6615
- UniProt: O95863
- Cellular Locus: Nucleus. Cytoplasm. Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs..
- Host: Rabbit
- Species Reactivity: Human, Mouse, Monkey
- Immunogen: The antiserum was produced against synthesized peptide derived from human SNAI1 around the phosphorylation site of Ser246. AA range:215-264
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
- Molecular Weight: 29kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.