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SNAI 1 rabbit pAb

CAT: 0855-ES3471-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3471-01Size:50 µL
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Background
Snail family transcriptional repressor 1 (SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008]
Description
Snail family transcriptional repressor 1 (SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008],
UniProt
O95863
Swiss Prot
O95863
Reactivity
Human; Mouse; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human SNAI1. AA range:215-264
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IP; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
29kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
29kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .
Other Product Names
SNAI1; SNAH; Zinc finger protein SNAI1; Protein snail homolog 1; Protein sna
Gene ID (Human)
6615

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