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ARHGAP22 rabbit pAb

CAT: 0855-ES6962-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6962-01Size:50 µL
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Background
This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Description
This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
UniProt
Q7Z5H3
Swiss Prot
Q7Z5H3
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human RHG22. AA range:565-614
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
77kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
77kD
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus . Mainly cytoplasmic. Some fraction is nuclear (By similarity) . .
Other Product Names
ARHGAP22; RHOGAP2; Rho GTPase-activating protein 22; Rho-type GTPase-activating protein 22
Gene ID (Human)
58504

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