ARHGAP22 Rabbit pAb (APR23165N)

CAT: 0882-APR23165N-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0882-APR23165N-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ARHGAP22 Rabbit pAb (APR23165N) .

Synonyms

ARHGAP22; RhoGAP2; RhoGap22

Gene ID

58504

UniProt

Q7Z5H3

Cellular Locus

Cytoplasm, Nucleus

Dilution

WB 1:500 - 1:2000

Form

Liquid

Buffer

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Molecular Weight

Calculated MW: 52kDa/66kDa/76kDa/77kDa/78kDa Observed MW: 77kDa

Storage Conditions

Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=58504

Uniprot URL

https://www.uniprot.org/uniprot/Q7Z5H3

AA Sequence

NVPAPGLVPGIPSVASMAWSGASSSESSVGGSLSSCTACRASDSSARSSLHTDWALEPSPLPSSSEDPKSLDLDHSMDEAGAGASNSEPSEPDSPTREHARRSEALQGLVTELRAELCRQRTEYERSVKRIEEGSADLRKR

UniProtKB · Q7Z5H3

Rho GTPase-activating protein 22

RHG22_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q7Z5H3
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: ARHGAP22
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: A0AVP7, A5YM75, B4DED8, B9EGA0, C9JDM2, O00152, Q6ZSB0

Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

AngiogenesisDifferentiationTranscriptionTranscription regulation

Domain

Coiled coil

Cellular component

CytoplasmNucleus

Molecular function

Developmental proteinGTPase activation

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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Alternative Products

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E45R23165N-50	ARHGAP22 Rabbit pAb
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MBS8109496-01	Anti-ARHGAP22 Antibody, Rabbit Polyclonal
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