RegisterLogin

PAK5/6 rabbit pAb

CAT: 0855-ES6873-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES6873-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]
Description
The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008],
Product Name Alternative
PAK7; KIAA1264; PAK5; Serine/threonine-protein kinase PAK 7; p21-activated kinase 5; PAK-5; p21-activated kinase 7; PAK-7; PAK6; PAK5; Serine/threonine-protein kinase PAK 6; PAK-5; p21-activated kinase 6; PAK-6
UniProt
Q9P286/Q9NQU5
Swiss Prot
Q9P286/Q9NQU5
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human PAK5/6. AA range:566-615
Target
PAK5/6
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
75kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
75kD
Fragment
IgG
Subcellular Location
Mitochondrion. Cytoplasm. Nucleus. Shuttles between the nucleus and the mitochondria, and mitochondrial localization is essential for the role in cell survival.
Other Product Names
PAK7; KIAA1264; PAK5; Serine/threonine-protein kinase PAK 7; p21-activated kinase 5; PAK-5; p21-activated kinase 7; PAK-7; PAK6; PAK5; Serine/threonine-protein kinase PAK 6; PAK-5; p21-activated kinase 6; PAK-6
Gene ID (Human)
57144/56924

Related Products

CatalogName
ES3145-01PAK5 rabbit pAb
ES6872-01PAK5/6 (phospho Ser602/S560) rabbit pAb
ES4458-01PAK4/5/6 rabbit pAb
ES6731-01Sox-6 rabbit pAb
ES5312-01Septin 6 rabbit pAb
ES7721-01TSSK 6 rabbit pAb
ES5624-01GRK 6 rabbit pAb
ES4482-01NHE-6 rabbit pAb
ES5806-01SR-6 rabbit pAb
ES8393-01CKR-6 rabbit pAb

Alternative Products

CatalogName
E28PT3574PAK5/6 Rabbit Polyclonal Antibody
MBS9145034-01PAK5 Rabbit pAb
E53P05511PAK5/6 S602/S560 Rabbit Polyclonal Antibody
E28PP0475PAK5/6 (phospho Ser602/S560) Rabbit Polyclonal Antibody
TA312682PAK5 Rabbit Polyclonal Antibody
APR22458N-01PAK5 Rabbit pAb (APR22458N)
SL0655R-01Rabbit Anti-PAK5 antibody
TA590312Rabbit Polyclonal PAK5 Antibody
327402-01PAK5/6
345174-01PAK5/6 discontinued

Popular Products