Products for Research Use Only

PKD1 (phospho Ser910) rabbit pAb

CAT: 0855-ES6785-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES6785-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009 [PubMed 19329994]) .[supplied by OMIM, Nov 2010]
Description
PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al. 2009 [PubMed 19329994]). [supplied by OMIM, Nov 2010],
UniProt
Q15139
Swiss Prot
Q15139
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PKD1/PKC mu around the phosphorylation site of Ser910. AA range:863-912
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
117kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
117kD
Fragment
IgG
Subcellular Location
Cytoplasm . Cell membrane . Golgi apparatus, trans-Golgi network . Translocation to the cell membrane is required for kinase activation.
Other Product Names
PRKD1; PKD; PKD1; PRKCM; Serine/threonine-protein kinase D1; Protein kinase C mu type; Protein kinase D; nPKC-D1; nPKC-mu
Gene ID (Human)
5587

UniProtKB · Q15139

Serine/threonine-protein kinase D1

KPCD1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15139
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PRKD1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.7.11.13
Processing
—
Secondary accessions
A6NL64, B2RAF6
Protein keywords

Biological process

AngiogenesisApoptosisDifferentiationImmunityInflammatory responseInnate immunityNeurogenesis

Ligand

ATP-bindingMagnesiumMetal-bindingNucleotide-bindingZinc

Cellular component

Cell membraneCytoplasmGolgi apparatusMembrane

Disease

Disease variantEctodermal dysplasia

Molecular function

KinaseSerine/threonine-protein kinaseTransferase

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger