PKD1 (phospho Tyr463) rabbit pAb
CAT:
855-ES6787-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PKD1 (phospho Tyr463) rabbit pAb
- Description: PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion (summary by Eiseler et al. 2009 [PubMed 19329994]). [supplied by OMIM, Nov 2010],
- Synonyms: PRKD1; PKD; PKD1; PRKCM; Serine/threonine-protein kinase D1; Protein kinase C mu type; Protein kinase D; nPKC-D1; nPKC-mu
- Gene ID: 5587
- UniProt: Q15139
- Cellular Locus: Cytoplasm. Cell membrane. Golgi apparatus, trans-Golgi network. Translocation to the cell membrane is required for kinase activation.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: The antiserum was produced against synthesized peptide derived from human PKD1/PKC mu around the phosphorylation site of Tyr463. AA range:429-478
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
- Molecular Weight: 130kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.