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PGD rabbit pAb

CAT: 0855-ES6578-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6578-02Size:100 µL
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Background
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]
Description
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015],
Product Name Alternative
PGD; PGDH; 6-phosphogluconate dehydrogenase; decarboxylating
UniProt
P52209
Swiss Prot
P52209
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PGD. AA range:71-120
Target
PGD
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
40kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
40kD
Fragment
IgG
Subcellular Location
Cytoplasm .
Other Product Names
PGD; PGDH; 6-phosphogluconate dehydrogenase; decarboxylating
Gene ID (Human)
5226

UniProtKB · P52209

6-phosphogluconate dehydrogenase, decarboxylating

6PGD_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P52209
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
PGD
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.1.1.44
Processing
—
Secondary accessions
A8K2Y9, B4DQJ8, Q9BWD8
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

Cytoplasm

Biological process

Gluconate utilizationPentose shunt

Ligand

NADP

Molecular function

Oxidoreductase

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