Products for Research Use Only
RegisterLogin

IκB-α rabbit pAb

CAT: 0855-ES6383-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES6383-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
Description
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011],
UniProt
P25963
Swiss Prot
P25963
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IkappaB-alpha. AA range:15-64
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
about 40kd
Storage Conditions
-20°C/1 year
Observed Molecular Weight
About 40kd
Fragment
IgG
Subcellular Location
Cytoplasm. Nucleus. Shuttles between the nucleus and the cytoplasm by a nuclear localization signal (NLS) and a CRM1-dependent nuclear export. .
Other Product Names
NFKBIA; IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3
Gene ID (Human)
4792

Related Products

CatalogName
ES1346-01IκB-β (phospho Ser23) rabbit pAb
ES6380-01IκB-α (phospho Tyr42) rabbit pAb
ES15405-01IκB-α (phospho-Ser32) rabbit pAb
ES6386-01IκB-ε (phospho Ser22) rabbit pAb
ES6384-01IκB-β (phospho Thr19) rabbit pAb
ES6381-01IκB-α (phospho Tyr305) rabbit pAb
ES1345-01IκB-α (phospho Ser32/S36) rabbit pAb
ES7542-01CA I rabbit pAb
ES5845-01IGF-I rabbit pAb
ES7457-01TTF-I rabbit pAb

Alternative Products

CatalogName
A11474IκBα Rabbit pAb
E2344534IκB-α Rabbit pAb
E60M0640IκB-α Rabbit mAb
E45R13086N-100IκBα Rabbit mAb
A25250-01IκB-ζ Rabbit pAb

Popular Products