IGF-I rabbit pAb

CAT: 0855-ES5845-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES5845-01Size:50 µL
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Background
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015]
Description
The protein encoded by this gene is similar to insulin in function and structure and is a member of a family of proteins involved in mediating growth and development. The encoded protein is processed from a precursor, bound by a specific receptor, and secreted. Defects in this gene are a cause of insulin-like growth factor I deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Sep 2015],
UniProt
P01343/P05019
Swiss Prot
P01343/P05019
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human IGF-I. AA range:100-149
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Extracellular region, extracellular space, plasma membrane, insulin-like growth factor binding protein complex, platelet alpha granule lumen, alphav-beta3 integrin-IGF-1-IGF1R complex, insulin-like growth factor ternary complex, exocytic vesicle
Other Product Names
IBP1; IGF-IA; IGF1A; IGFI; insulin-like growth factor 1; insulin-like growth factor IA; mechano growth factor; MGF; somatomedin C
Gene ID (Human)
3479

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