MEF-2 (phospho Thr312) rabbit pAb

• Background:

  The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1) . Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]

• Description:

  The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],

• Synonyms:

  MEF2A; MEF2; Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1

• Gene ID:

  4205

• UniProt:

  Q02078

• Cellular Locus:

  Nucleus.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human MEF2A around the phosphorylation site of Thr312. AA range:279-328

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, IP, ELISA

• Validated Applications:

  WB, IHC, IF, IP, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunoprecipitation: 2-5 ug/mg lysate. ELISA: 1/20000. Not yet tested in other applications.

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  Nucleus .

• Other Product Names:

  MEF2A; MEF2; Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1

• Gene ID (Human):

  4205

• SwissProt (Human):

  Q02078