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MEF-2 (phospho Ser408) rabbit pAb

CAT: 0855-ES1509-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES1509-01Size:50 µL
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Background
The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1) . Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
Description
The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010],
Product Name Alternative
MEF2A; MEF2; Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1
UniProt
Q02078
Swiss Prot
Q02078
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MEF2A around the phosphorylation site of Ser408. AA range:374-423
Target
MEF-2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
55kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
55kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
MEF2A; MEF2; Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1
Gene ID (Human)
4205

UniProtKB · Q02078

Myocyte-specific enhancer factor 2A

MEF2A_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q02078
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MEF2A
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B4DFQ7, F6XG23, O43814, Q14223, Q14224, Q59GX4, Q7Z6C9, Q96D14
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDevelopmental proteinDNA-binding

Coding sequence diversity

Alternative splicing

Biological process

ApoptosisDifferentiationNeurogenesisTranscriptionTranscription regulation

Disease

Disease variant

Cellular component

Nucleus

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