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Laminin β-3 rabbit pAb

CAT: 0855-ES6083-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6083-01Size:50 µL
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Background
The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Description
The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Product Name Alternative
LAMB3; LAMNB1; Laminin subunit beta-3; Epiligrin subunit bata; Kalinin B1 chain; Kalinin subunit beta; Laminin B1k chain; Laminin-5 subunit beta; Nicein subunit beta
UniProt
Q13751
Swiss Prot
Q13751
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human LAMB3. AA range:671-720
Target
Laminin β-3
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane.
Other Product Names
LAMB3; LAMNB1; Laminin subunit beta-3; Epiligrin subunit bata; Kalinin B1 chain; Kalinin subunit beta; Laminin B1k chain; Laminin-5 subunit beta; Nicein subunit beta
Gene ID (Human)
3914

UniProtKB · Q13751

Laminin subunit beta-3

LAMB3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13751
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LAMB3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
D3DT88, O14947, Q14733, Q9UJK4, Q9UJL1
Protein keywords

Disease

Amelogenesis imperfectaDisease variantEpidermolysis bullosa

Cellular component

Basement membraneExtracellular matrixSecreted

Biological process

Cell adhesion

Domain

Coiled coilLaminin EGF-like domainRepeatSignal

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

Disulfide bondGlycoprotein

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