Products for Research Use Only
RegisterLogin

Laminin α-3 rabbit pAb

CAT: 0855-ES6075-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES6075-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014]
Description
The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014],
Product Name Alternative
LAMA3; LAMNA; Laminin subunit alpha-3; Epiligrin 170 kDa subunit; E170; Epiligrin subunit alpha; Kalinin subunit alpha; Laminin-5 subunit alpha; Laminin-6 subunit alpha; Laminin-7 subunit alpha; Nicein subunit alpha
UniProt
Q16787
Swiss Prot
Q16787
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human LAMA3. AA range:2571-2620
Target
Laminin α-3
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
120 60kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
120 60kD
Fragment
IgG
Subcellular Location
Secreted, extracellular space, extracellular matrix, basement membrane. Major component.
Other Product Names
LAMA3; LAMNA; Laminin subunit alpha-3; Epiligrin 170 kDa subunit; E170; Epiligrin subunit alpha; Kalinin subunit alpha; Laminin-5 subunit alpha; Laminin-6 subunit alpha; Laminin-7 subunit alpha; Nicein subunit alpha
Gene ID (Human)
3909

UniProtKB · Q16787

Laminin subunit alpha-3

LAMA3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q16787
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LAMA3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B0YJ33, Q13679, Q13680, Q6VU67, Q6VU68, Q6VU69, Q76E14, Q96TG0
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Basement membraneExtracellular matrixSecreted

Biological process

Cell adhesion

Domain

Coiled coilLaminin EGF-like domainRepeatSignal

Disease

Disease variantEpidermolysis bullosa

PTM

Disulfide bondGlycoprotein

Technical term

Proteomics identificationReference proteome

Related Products

CatalogName
ES6087-01Laminin-R rabbit pAb
ES6084-01Laminin γ-1 rabbit pAb
ES2698-01Laminin α-4 rabbit pAb
ES6077-01Laminin α-5 rabbit pAb
ES6074-01Laminin α-2 rabbit pAb
ES6082-01Laminin β-2 rabbit pAb
ES4109-01Laminin γ-2 rabbit pAb
ES5594-01Laminin α-1 rabbit pAb
ES2699-01Laminin β-1 Rabbit Polyclonal Antibody
ES1540-0114-3-3 β rabbit pAb

Alternative Products

CatalogName
APA1696-01Laminin Rabbit pAb
MBS223140-01RABBIT ANTI LAMININ
MBS316309-01Rabbit A' Mouse Laminin
ELA-E2207RbRabbit Laminin Gamma1/ Laminin B2 ELISA Kit
NBP1-87717Rabbit Polyclonal Laminin S/Laminin beta 2 Antibody
NB300-144Rabbit Polyclonal Laminin Antibody
MBS731004-01Rabbit Laminin ELISA Kit
R1153BLaminin Rabbit Polyclonal Antibody
62270-01Laminin α-1 Rabbit pAb
E2251534Laminin γ-2 Rabbit pAb

Popular Products