EMR2 rabbit pAb

CAT: 0855-ES5733-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES5733-01Size:50 µL
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Background
This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Description
This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012],
Product Name Alternative
EMR2; EGF-like module-containing mucin-like hormone receptor-like 2; EGF-like module receptor 2; CD antigen CD312
UniProt
Q9UHX3
Swiss Prot
Q9UHX3
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human EMR2. AA range:765-814
Target
EMR2
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
85kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
85kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein. Cell projection, ruffle membrane ; Multi-pass membrane protein. Localized at the leading edge of migrating cells. .
Other Product Names
EMR2; EGF-like module-containing mucin-like hormone receptor-like 2; EGF-like module receptor 2; CD antigen CD312
Gene ID (Human)
30817

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