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EMR4 rabbit pAb

CAT: 0855-ES2259-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2259-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008]
Description
This gene is a member of the EGF-TM7 receptor gene family which is thought to play a role in leukocyte adhesion and migration. In other vertebrates, including nonhuman primates, this gene encodes a protein containing N-terminal EGF domains and a C-terminal transmembrane domain. Sequence evidence for the human gene, however, indicates nucleotide deletion in the genomic sequence would result in frameshift and early termination of translation. A protein expressed by this gene would be soluble rather than expressed on the cell surface. As the encoded protein has not been detected, this gene may represent a transcribed pseudogene. [provided by RefSeq, Aug 2008],
UniProt
Q86SQ3
Swiss Prot
Q86SQ3
Reactivity
Human; Monkey
Immunogen
The antiserum was produced against synthesized peptide derived from human EMR4P. AA range:101-150
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
55kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
55kD
Fragment
IgG
Subcellular Location
[Isoform 1]: Cell membrane ; Multi-pass membrane protein .; [Isoform 2]: Secreted .
Other Product Names
EMR4P; EMR4; GPR127; PGR16; Putative EGF-like module-containing mucin-like hormone receptor-like 4; EGF-like module receptor 4; G-protein coupled receptor 127; G-protein coupled receptor PGR16
Gene ID (Human)
326342

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