Pdcd-4 (phospho Ser67) rabbit pAb
CAT:
855-ES5549-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Pdcd-4 (phospho Ser67) rabbit pAb
- Description: This gene is a tumor suppressor and encodes a protein that binds to the eukaryotic translation initiation factor 4A1 and inhibits its function by preventing RNA binding. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010],
- Synonyms: PDCD4; H731; Programmed cell death protein 4; Neoplastic transformation inhibitor protein; Nuclear antigen H731-like; Protein 197/15a
- Gene ID: 27250
- UniProt: Q53EL6
- Cellular Locus: Nucleus. Cytoplasm. Shuttles between the nucleus and cytoplasm (By similarity). Predominantly nuclear under normal growth conditions, and when phosphorylated at Ser-457 (PubMed:16357133)..
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat, Monkey
- Immunogen: The antiserum was produced against synthesized peptide derived from human PDCD4 around the phosphorylation site of Ser67. AA range:33-82
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
- Molecular Weight: 56kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.