Kv3.4 (phospho Ser15) rabbit pAb

• Background:

  The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]

• Description:

  The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. It generates atypical voltage-dependent transient current that may be important for neuronal excitability. Multiple transcript variants have been found for this gene. [provided by RefSeq, Jul 2010],

• Synonyms:

  KCNC4; Potassium voltage-gated channel subfamily C member 4; KSHIIIC; Voltage-gated potassium channel subunit Kv3.4

• Gene ID:

  3749

• UniProt:

  Q03721

• Cellular Locus:

  Membrane; Multi-pass membrane protein.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized phospho-peptide around the phosphorylation site of human Kv3.4 (phospho Ser15)

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  IHC, IF, ELISA

• Validated Applications:

  IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  Membrane; Multi-pass membrane protein.

• Other Product Names:

  KCNC4; Potassium voltage-gated channel subfamily C member 4; KSHIIIC; Voltage-gated potassium channel subunit Kv3.4

• Gene ID (Human):

  3749

• SwissProt (Human):

  Q03721