INPP5J rabbit pAb

INPP5J rabbit pAb

• Description: Catalytic activity: 1D-myo-inositol 1, 3, 4, 5-tetrakisphosphate + H (2)O = 1D-myo-inositol 1, 3, 4-trisphosphate + phosphate. Catalytic activity: D-myo-inositol 1, 4, 5-trisphosphate + H (2)O = myo-inositol 1, 4-bisphosphate + phosphate. Domain: The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein. function: Inositol 5-phosphatase, which converts inositol 1, 4, 5-trisphosphate to inositol 1, 4-bisphosphate. Also converts phosphatidylinositol 4, 5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1, 3, 4, 5-tetrakisphosphate to inositol 1, 3, 4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles. PTM: Phosphorylated at Ser/Thr residues. similarity: Belongs to the inositol-1, 4, 5-trisphosphate 5-phosphatase type II family. subcellular location: Predominantly localized to membrane ruffles.
• Synonyms: INPP5J; PIB5PA; PIPP; Phosphatidylinositol 4; 5-bisphosphate 5-phosphatase A; Inositol polyphosphate 5-phosphatase J
• Gene ID: 27124
• UniProt: Q15735
• Cellular Locus: Cytoplasm. Predominantly localized to membrane ruffles..
• Host: Rabbit
• Species Reactivity: Human, Rat
• Immunogen: Synthesized peptide derived from INPP5J . at AA range: 850-930
• Clonality: Polyclonal
• Validated Applications: IHC, IF, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.