DECR2 rabbit pAb

• Background :

  Catalytic activity:Trans-2,3-didehydroacyl-CoA + NADP (+) = trans, trans-2,3,4,5-tetradehydroacyl-CoA + NADPH., function:Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid., similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family., similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.

• Description :

  Catalytic activity: Trans-2, 3-didehydroacyl-CoA + NADP (+) = trans, trans-2, 3, 4, 5-tetradehydroacyl-CoA + NADPH. function: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2, 4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2, 4-dienoyl-CoAs, but also towards 2, 4, 7, 10, 13, 16, 19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2, 4-dienoyl-CoA reductase subfamily.

• UniProt :

  Q9NUI1

• Swiss Prot :

  Q9NUI1

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human DECR2. AA range:217-266

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  36kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  36kD

• Fragment :

  IgG

• Subcellular Location :

  Peroxisome .

• Other Product Names :

  DECR2; PDCR; Peroxisomal 2; 4-dienoyl-CoA reductase; pDCR; 2,4-dienoyl-CoA reductase 2

• Gene ID (Human) :

  26063