CEP152 rabbit pAb

• Background:

  Centrosomal protein 152 (CEP152) Homo sapiens This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4) . Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]

• Description:

  Centrosomal protein 152 (CEP152) Homo sapiens This gene encodes a protein that is thought to be involved with centrosome function. Mutations in this gene have been associated with primary microcephaly (MCPH4). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010],

• UniProt:

  O94986

• Swiss Prot:

  O94986

• Reactivity:

  Human; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human CEP152. AA range:841-890

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight:

  140kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  140kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Colocalizes with CDK5RAP2, WDR62 and CEP63 in a discrete ring around the proximal end of the parental centriole. At this site, a cohesive structure is predicted to engage parental centrioles and procentrioles (PubMed:21983783, PubMed:26297806) . Localizes to the deuterosome (By similarity) . Localizes to pericentriolar material (PCM) (PubMed:26337392) . .

• Other Product Names:

  CEP152; KIAA0912; Centrosomal protein of 152 kDa; Cep152

• Gene ID (Human):

  22995