Products for Research Use Only
RegisterLogin

Defensin α4 rabbit pAb

CAT: 0855-ES4990-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES4990-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Defensin alpha 4 (DEFA4) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014]
Description
Defensin alpha 4 (DEFA4) Homo sapiens Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014],
UniProt
P12838
Swiss Prot
P12838
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Defensin alpha4. AA range:27-76
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted . Cytoplasmic vesicle, secretory vesicle . Stored as mature peptide in neutrophil granules. .
Other Product Names
DEFA4; DEF4; Neutrophil defensin 4; Defensin; alpha 4; HNP-4; HP-4
Gene ID (Human)
1669

Related Products

CatalogName
ES4988-01Defensin α1 rabbit pAb
ES4989-01Defensin α3 rabbit pAb
ES18063-01Beta-defensin 4A Rabbit pAb
ES18064-01Beta-defensin 1 Rabbit pAb
ES3148-01PAR-4 rabbit pAb
ES7853-01VAMP-4 rabbit pAb
ES4282-01FGF-4 rabbit pAb
ES8517-01TIMP-4 rabbit pAb
ES5708-01Fibulin-4 rabbit pAb
ES4707-01CKR-4 rabbit pAb

Alternative Products

CatalogName
APA2014-01Alpha Defensin 5 Rabbit pAb
MBS7256830-01Rabbit Defensin Alpha ELISA Kit
MBS9468572-01beta Defensin 1 Rabbit mAb
APRab09903-01Defensin α3 Rabbit Polyclonal Antibody
GTR10445836Rabbit β Defensin 14 ELISA kit
GTR10399948Rabbit β Defensin 3 ELISA kit
E47R1163Defensin beta 1 Rabbit pAb
E47R1296Defensin beta 2 Rabbit pAb
E2382398Beta Defensin 1 Rabbit pAb
APRab09902-01Defensin α1 Rabbit Polyclonal Antibody

Popular Products