Beta-defensin 1 Rabbit pAb

• Background:

  Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008]

• Description:

  Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis. [provided by RefSeq, Jul 2008],

• Synonyms:

  Beta-defensin 1 (BD-1;hBD-1;Defensin, beta 1)

• Gene ID:

  1672

• UniProt:

  P60022

• Cellular Locus:

  Secreted. Membrane. Associates with tumor cell membrane-derived microvesicles (PubMed:23938203)..

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse,

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthesized peptide derived from human Beta-defensin 1 AA range: 1-50

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  IHC, ELISA

• Validated Applications:

  IHC, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  IHC-p 1:50-200, ELISA (peptide) 1:5000-20000

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  Secreted . Membrane . Associates with tumor cell membrane-derived microvesicles (PubMed:23938203) . .

• Other Product Names:

  Beta-defensin 1 (BD-1; hBD-1; Defensin, beta 1)

• Gene ID (Human):

  1672

• SwissProt (Human):

  P60022