VAMP-4 rabbit pAb

• Background:

  Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP) /synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008]

• Description:

  Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008],

• Synonyms:

  VAMP4; Vesicle-associated membrane protein 4; VAMP-4

• Gene ID:

  8674

• UniProt:

  O75379

• Cellular Locus:

  Golgi apparatus, trans-Golgi network membrane ; Single-pass type IV membrane protein. Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse

• Reactivity:

  Human; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human VAMP4. AA range:1-50

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  IF, ELISA

• Validated Applications:

  IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  Golgi apparatus, trans-Golgi network membrane ; Single-pass type IV membrane protein . Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG) . Not found on the mature secretory organelles.

• Other Product Names:

  VAMP4; Vesicle-associated membrane protein 4; VAMP-4

• Gene ID (Human):

  8674

• SwissProt (Human):

  O75379