CYP21A2 rabbit pAb

CAT: 0855-ES4953-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES4953-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Cytochrome P450 family 21 subfamily A member 2 (CYP21A2) Homo sapiens This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Description
Cytochrome P450 family 21 subfamily A member 2 (CYP21A2) Homo sapiens This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
UniProt
P08686
Swiss Prot
P08686
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from the Internal region of human CYP21A2.
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
55kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
55kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane; Peripheral membrane protein . Microsome membrane ; Peripheral membrane protein .
Other Product Names
CYP21A2; CYP21; CYP21B; Steroid 21-hydroxylase; 21-OHase; Cytochrome P-450c21; Cytochrome P450 21; Cytochrome P450 XXI; Cytochrome P450-C21; Cytochrome P450-C21B
Gene ID (Human)
1589

Related Products

CatalogName
ES4921-01CYP1A2 rabbit pAb
ES4947-01CYP11A1 rabbit pAb
ES2097-01CYP2A13 rabbit pAb
ES2095-01CYP26A1 rabbit pAb
ES2096-01CYP27A1 rabbit pAb
ES4955-01CYP24A1 rabbit pAb
ES6893-01CYP20A1 rabbit pAb
ES2093-01CYP1A1/2 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb

Alternative Products

CatalogName
E47R2443CYP21A2 Rabbit pAb
MBS8555149-01CYP21A2 (Center) Rabbit pAb
MBS9512359-01CYP21A2 Rabbit Polyclonal Antibody
NBP2-13893Rabbit Polyclonal CYP21A2 Antibody
SL2443R-01Rabbit Anti-CYP21A2 antibody
PAV6460Rabbit Anti-CYP21A2 Polyclonal Antibody
E2616486CYP21A2 (N-term) Rabbit pAb
CSB-CL006400HU1CYP21A2

Popular Products