CYP26A1 rabbit pAb
CAT:
855-ES2095-01
Size:
50 μL
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CYP26A1 rabbit pAb
- Description: Cytochrome P450 family 26 subfamily A member 1 (CYP26A1) Homo sapiens This gene encodes a member of the Cytochrome P450 superfamily of enzymes. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008],
- Synonyms: CYP26A1; CYP26; P450RAI1; Cytochrome P450 26A1; Cytochrome P450 retinoic acid-inactivating 1; Cytochrome P450RAI; hP450RAI; Retinoic acid 4-hydroxylase; Retinoic acid-metabolizing cytochrome
- Gene ID: 1592
- UniProt: O43174
- Cellular Locus: Endoplasmic reticulum membrane ; Peripheral membrane protein. Microsome membrane ; Peripheral membrane protein.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: The antiserum was produced against synthesized peptide derived from human Cytochrome P450 26A1. AA range:251-300
- Clonality: Polyclonal
- Validated Applications: WB, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
- Molecular Weight: 56kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.