Products for Research Use Only
RegisterLogin

MAN1B1 rabbit pAb

CAT: 0855-ES4624-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES4624-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1,2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011]
Description
This gene encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N-glycan biosynthesis, and is a class I alpha-1, 2-mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N-glycan trimming to Man5-6GlcNAc2 in the endoplasmic-reticulum-associated degradation pathway. Mutations in this gene cause autosomal-recessive intellectual disability. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 11. [provided by RefSeq, Dec 2011],
Product Name Alternative
MAN1B1; Endoplasmic reticulum mannosyl-oligosaccharide 1; 2-alpha-mannosidase; ER alpha-1,2-mannosidase; ER mannosidase 1; ERMan1; Man9GlcNAc2-specific-processing alpha-mannosidase; Mannosidase alpha class 1B member 1
UniProt
Q9UKM7
Swiss Prot
Q9UKM7
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from MAN1B1 . at AA range: 100-180
Target
MAN1B1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
80kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
80kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
Other Product Names
MAN1B1; Endoplasmic reticulum mannosyl-oligosaccharide 1; 2-alpha-mannosidase; ER alpha-1,2-mannosidase; ER mannosidase 1; ERMan1; Man9GlcNAc2-specific-processing alpha-mannosidase; Mannosidase alpha class 1B member 1
Gene ID (Human)
11253

Related Products

CatalogName
ES10653-01MANS1 rabbit pAb
ES19268-01MANBA rabbit pAb
ES15044-01MAN1 rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb
ES20829-01ATG4a Rabbit rabbit pAb
ES20658-01NM23A Rabbit rabbit pAb

Alternative Products

CatalogName
E47R18644MAN1B1 Rabbit pAb
TA312707MAN1B1 Rabbit Polyclonal Antibody
SL18644R-01Rabbit Anti-MAN1B1 antibody
APR20352N-01MAN1B1 Rabbit pAb (APR20352N)
GTR18051590MAN1B1 rabbit pAb Antibody
GTR17709480MAN1B1 Rabbit Polyclonal Antibody (FITC)
GTR17795709MAN1B1 Rabbit Polyclonal Antibody (AP)
GTR17817718MAN1B1 Rabbit Polyclonal Antibody (APC)
GTR18472913MAN1B1 Rabbit Polyclonal Antibody (BF405)
GTR18472891MAN1B1 Rabbit Polyclonal Antibody (BF555)

Popular Products