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MAN1 rabbit pAb

CAT: 0855-ES15044-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES15044-01Size:50 µL
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Background
This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.[provided by RefSeq, Nov 2009]
Description
This locus encodes a LEM domain-containing protein. The encoded protein functions to antagonize transforming growth factor-beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis. [provided by RefSeq, Nov 2009],
UniProt
Q9Y2U8
Swiss Prot
Q9Y2U8
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human MAN1 AA range: 61-111
Target
MAN1
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Nucleus inner membrane ; Multi-pass membrane protein .
Gene ID (Human)
23592

UniProtKB · Q9Y2U8

Inner nuclear membrane protein Man1

MAN1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y2U8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
LEMD3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9NT47, Q9NYA5
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Disease

Disease variant

Molecular function

DNA-binding

Cellular component

MembraneNucleus

Domain

TransmembraneTransmembrane helix

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