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USP16 rabbit pAb

CAT: 0855-ES4515-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES4515-02Size:100 µL
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Background
This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Description
This gene encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase/anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
Product Name Alternative
USP16; MSTP039; Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme 16; Ubiquitin thioesterase 16; Ubiquitin-processing protease UBP-M; Ubiquitin-specific-processing protease 16
UniProt
Q9Y5T5
Swiss Prot
Q9Y5T5
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human USP16.
Target
USP16
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
93kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
93kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
USP16; MSTP039; Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme 16; Ubiquitin thioesterase 16; Ubiquitin-processing protease UBP-M; Ubiquitin-specific-processing protease 16
Gene ID (Human)
10600

UniProtKB · Q9Y5T5

Ubiquitin carboxyl-terminal hydrolase 16

UBP16_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9Y5T5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
USP16
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.4.19.12
Processing
—
Secondary accessions
A8MU43, B3KN13, B4DFV8, B4DY37, D3DSD9, Q53GP7, Q53HA0, Q5VKN8, Q8NEL3, Q9H3E6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

ActivatorChromatin regulatorHydrolaseProteaseThiol protease

Coding sequence diversity

Alternative splicingChromosomal rearrangement

Biological process

Cell cycleCell divisionMitosisTranscriptionTranscription regulationUbl conjugation pathway

Cellular component

CytoplasmNucleus

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Domain

Zinc-finger

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