USP11 rabbit pAb

CAT: 0855-ES4401-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES4401-01Size:50 µL
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Background
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23 [provided by RefSeq, Jul 2008]
Description
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11. 23 [provided by RefSeq, Jul 2008],
Product Name Alternative
USP11; UHX1; Ubiquitin carboxyl-terminal hydrolase 11; Deubiquitinating enzyme 11; Ubiquitin thioesterase 11; Ubiquitin-specific-processing protease 11
UniProt
P51784
Swiss Prot
P51784
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human USP11.
Target
USP11
Clonality
Polyclonal
Source
Rabbit
Applications
IF; WB; ELISA
Concentration
1 mg/ml
Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
105kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
105kD
Fragment
IgG
Subcellular Location
Nucleus . Cytoplasm . Chromosome . Predominantly nuclear (PubMed:12084015, PubMed:15314155) . Associates with chromatin (PubMed:20601937, PubMed:20233726) . .
Other Product Names
USP11; UHX1; Ubiquitin carboxyl-terminal hydrolase 11; Deubiquitinating enzyme 11; Ubiquitin thioesterase 11; Ubiquitin-specific-processing protease 11
Gene ID (Human)
8237

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