SAMHD1 rabbit pAb

• Background:

  SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) Homo sapiens This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010]

• Description:

  SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) Homo sapiens This gene may play a role in regulation of the innate immune response. The encoded protein is upregulated in response to viral infection and may be involved in mediation of tumor necrosis factor-alpha proinflammatory responses. Mutations in this gene have been associated with Aicardi-Goutieres syndrome. [provided by RefSeq, Mar 2010],

• UniProt:

  Q9Y3Z3

• Swiss Prot:

  Q9Y3Z3

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  The antiserum was produced against synthesized peptide derived from the Internal region of human SAMHD1. AA range:431-480

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight:

  72kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  72kD

• Fragment:

  IgG

• Subcellular Location:

  Nucleus . Chromosome . Localizes to sites of DNA double-strand breaks in response to DNA damage. .

• Other Product Names:

  SAMHD1; MOP5; SAM domain and HD domain-containing protein 1; Dendritic cell-derived IFNG-induced protein; DCIP; Monocyte protein 5; MOP-5

• Gene ID (Human):

  25939