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CD248 rabbit pAb

CAT: 0855-ES3997-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES3997-01Size:50 µL
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Background
Function:May play a role in tumor angiogenesis., online information:Endosialin, PTM:May be N-glycosylated., PTM:O-glycosylated with sialylated oligosaccharides., similarity:Contains 1 C-type lectin domain., similarity:Contains 1 EGF-like domain., similarity:Contains 1 Sushi (CCP/SCR) domain., tissue specificity:Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.
Description
Function: May play a role in tumor angiogenesis. online information: Endosialin, PTM: May be N-glycosylated. PTM: O-glycosylated with sialylated oligosaccharides. similarity: Contains 1 C-type lectin domain. similarity: Contains 1 EGF-like domain. similarity: Contains 1 Sushi (CCP/SCR) domain. tissue specificity: Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.
Product Name Alternative
CD248; CD164L1; TEM1; Endosialin; Tumor endothelial marker 1; CD248
UniProt
Q9HCU0
Swiss Prot
Q9HCU0
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CD248. AA range:341-390
Target
CD248
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
80kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
80kD
Fragment
IgG
Subcellular Location
Membrane ; Single-pass type I membrane protein .
Other Product Names
CD248; CD164L1; TEM1; Endosialin; Tumor endothelial marker 1; CD248
Gene ID (Human)
57124

UniProtKB · Q9HCU0

Endosialin

CD248_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9HCU0
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CD248
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q2M2V5, Q3SX55, Q96KB6
Protein keywords

Coding sequence diversity

Alternative splicing

Ligand

CalciumLectin

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

EGF-like domainSignalTransmembraneTransmembrane helix

Cellular component

Membrane

Technical term

Proteomics identificationReference proteome