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TLE4 rabbit pAb

CAT: 0855-ES3615-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES3615-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Caution:Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed:15302935) would require further confirmation., function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES., similarity:Belongs to the WD repeat Groucho/TLE family., similarity:Contains 7 WD repeats., subunit:Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2., tissue specificity:In all tissues examined, mostly in brain, and muscle.
Description
Caution: Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed: 15302935) would require further confirmation. function: Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. similarity: Belongs to the WD repeat Groucho/TLE family. similarity: Contains 7 WD repeats. subunit: Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2. tissue specificity: In all tissues examined, mostly in brain, and muscle.
UniProt
Q04727
Swiss Prot
Q04727
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human TLE4. AA range:161-210
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Molecular Weight
83kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
83kD
Fragment
IgG
Subcellular Location
Nucleus.
Other Product Names
TLE4; KIAA1261; Transducin-like enhancer protein 4
Gene ID (Human)
7091

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