SSH3 rabbit pAb

• Background:

  The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .[supplied by OMIM, Mar 2008]

• Description:

  The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al. 2002 [PubMed 11832213]). [supplied by OMIM, Mar 2008],

• UniProt:

  Q8TE77

• Swiss Prot:

  Q8TE77

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human SSH3. AA range:357-406

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight:

  74kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  74kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm, cytoskeleton . Nucleus .

• Other Product Names:

  SSH3; SSH3L; Protein phosphatase Slingshot homolog 3; SSH-like protein 3; SSH-3L; hSSH-3L

• Gene ID (Human):

  54961