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SSH3 (phospho-Ser37) rabbit pAb

CAT: 0855-ES12946-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES12946-01Size:50 µL
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Background
The ADF (actin-depolymerizing factor) /cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329) . The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]) .[supplied by OMIM, Mar 2008]
Description
The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al. 2002 [PubMed 11832213]). [supplied by OMIM, Mar 2008],
UniProt
Q8TE77
Swiss Prot
Q8TE77
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized phosho peptide around human SSH3 (Ser37)
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:1000-2000
Molecular Weight
74kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
74kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton . Nucleus .
Other Product Names
Protein phosphatase Slingshot homolog 3 (EC 3.1.3.16) (EC 3.1.3.48) (SSH-like protein 3) (SSH-3L) (hSSH-3L)
Gene ID (Human)
54961

UniProtKB · Q8TE77

Protein phosphatase Slingshot homolog 3

SSH3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8TE77
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SSH3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.3.16, 3.1.3.48
Processing
—
Secondary accessions
Q6PK42, Q76I75, Q8N9L8, Q8WYL0, Q9NV45, Q9NWZ7
Protein keywords

PTM

AcetylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmCytoskeletonNucleus

Molecular function

HydrolaseProtein phosphatase

Technical term

Proteomics identificationReference proteome

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