NOS2 rabbit pAb

• Background:

  Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

• Description:

  Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008],

• UniProt:

  P35228

• Swiss Prot:

  P35228

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human iNOS. AA range:117-166

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IF; WB; IHC; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  IF: 1:50-200 WB 1:500-2000, ELISA 1:10000-20000 IHC 1:50-300

• Molecular Weight:

  131kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  131kD

• Fragment:

  IgG

• Subcellular Location:

  Cytoplasm, cytosol . Localizes as discrete foci scattered throughout the cytosol and in the presence of SPSB1 and SPSB4, exhibits a more diffuse cytosolic localization. .

• Other Product Names:

  NOS2; NOS2A; Nitric oxide synthase; inducible; Hepatocyte NOS; HEP-NOS; Inducible NO synthase; Inducible NOS; iNOS; NOS type II; Peptidyl-cysteine S-nitrosylase NOS2

• Gene ID (Human):

  4843