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MYH14 rabbit pAb

CAT: 0855-ES2875-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2875-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14) . Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Description
This gene encodes a member of the myosin superfamily. The protein represents a conventional non-muscle myosin; it should not be confused with the unconventional myosin-14 (MYO14). Myosins are actin-dependent motor proteins with diverse functions including regulation of cytokinesis, cell motility, and cell polarity. Mutations in this gene result in one form of autosomal dominant hearing impairment. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
UniProt
Q7Z406
Swiss Prot
Q7Z406
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MYH14. AA range:1051-1100
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
228kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
228kD
Fragment
IgG
Subcellular Location
Stress fiber, cytosol, brush border, membrane, myosin complex, myosin II complex, axon, growth cone, actomyosin, myelin sheath, extracellular exosome, myosin II filament
Other Product Names
MYH14; KIAA2034; FP17425; Myosin-14; Myosin heavy chain 14; Myosin heavy chain; non-muscle IIc; Non-muscle myosin heavy chain IIc; NMHC II-C
Gene ID (Human)
79784

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