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MRP-S27 rabbit pAb

CAT: 0855-ES2850-01Size: 50 µLDry Ice: NoHazardous: No
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Background
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3) . Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013]
Description
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that may be a functional partner of the death associated protein 3 (DAP3). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013],
Product Name Alternative
MRPS27; KIAA0264; 28S ribosomal protein S27; mitochondrial; MRP-S27; S27mt
UniProt
Q92552
Swiss Prot
Q92552
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MRPS27. AA range:16-65
Target
MRP-S27
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Buffer
-20°C/1 year
Molecular Weight
48kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
48kD
Fragment
IgG
Subcellular Location
Cytoplasm . Mitochondrion .
Other Product Names
MRPS27; KIAA0264; 28S ribosomal protein S27; mitochondrial; MRP-S27; S27mt
Gene ID (Human)
23107

UniProtKB · Q92552

Small ribosomal subunit protein mS27

RT27_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q92552
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MRPS27
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
B4DRT2, Q6P1S1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Domain

Coiled coilRepeatTransit peptide

Cellular component

CytoplasmMitochondrion

Molecular function

RibonucleoproteinRibosomal proteinRNA-bindingrRNA-bindingtRNA-binding

Biological process

Translation regulation

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