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MRP rabbit pAb

CAT: 0855-ES9040-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES9040-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MARCKS like 1 (MARCKSL1) Homo sapiens This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10. [provided by RefSeq, Jun 2012]
Description
MARCKS like 1 (MARCKSL1) Homo sapiens This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10. [provided by RefSeq, Jun 2012],
UniProt
P49006
Swiss Prot
P49006
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from human protein . at AA range: 1-80
Target
MRP
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
21kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
21kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton . Cell membrane ; Lipid-anchor . Associates with the membrane via the insertion of the N-terminal N-myristoyl chain and the partial insertion of the effector domain. Association of the effector domain with membranes may be regulated by Ca (2+) /calmodulin. Colocalizes with F-actin at the leading edge of migrating cells (By similarity) . In prostate cancers, shows strong expression at apical and/or basal regions of the cell and also has weak cytoplasmic expression (PubMed:22751924) . .
Gene ID (Human)
65108

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