Products for Research Use Only
RegisterLogin

MAD2 rabbit pAb

CAT: 0855-ES2738-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES2738-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008]
Description
MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14. [provided by RefSeq, Jul 2008],
UniProt
Q13257
Swiss Prot
Q13257
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MAD2L1. AA range:91-140
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IP; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IP 1:200-500 ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
25kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
25kD
Fragment
IgG
Subcellular Location
Nucleus . Chromosome, centromere, kinetochore. Cytoplasm . Cytoplasm, cytoskeleton, spindle pole. Recruited by MAD1L1 to unattached kinetochores (Probable) . Recruited to the nuclear pore complex by TPR during interphase. Recruited to kinetochores in late prometaphase after BUB1, CENPF, BUB1B and CENPE. Kinetochore association requires the presence of NEK2. Kinetochore association is repressed by UBD. Sequestered to the cytoplasm upon interaction with isoform 3 of MAD1L1 (PubMed:19010891) . .
Other Product Names
MAD2L1; MAD2; Mitotic spindle assembly checkpoint protein MAD2A; HsMAD2; Mitotic arrest deficient 2-like protein 1; MAD2-like protein 1
Gene ID (Human)
4085

Related Products

CatalogName
ES19479-01MAD3 rabbit pAb
ES7712-01MAD1 rabbit pAb
ES2739-01MADD rabbit pAb
ES4518-01Mad 4 rabbit pAb
ES7711-01MAD1 (phospho Ser428) rabbit pAb
ES4666-01RAB3IP rabbit pAb
ES20751-01Gab1 Rabbit rabbit pAb
ES20703-01JAK2 Rabbit rabbit pAb
ES20758-01ERK1 Rabbit rabbit pAb
ES20830-01ATG14L Rabbit rabbit pAb

Alternative Products

CatalogName
GTR18220341-01Rabbit MAD2 Antibody
MBS9145048-01MAD2/MAD2L1 Rabbit pAb
GTR18213958-01Rabbit MAD2 IHC Antibody
A11469-01MAD2/MAD2L1 Rabbit mAb
APRab13553-01MAD2 Rabbit Polyclonal Antibody
DL90703A-01Rabbit anti-MAD2 Antibody
AMR12540N-01MAD2/MAD2L1 Rabbit mAb (AMR12540N)
APR29800N-01MAD2/MAD2L1 Rabbit pAb (APR29800N)
322868-01MAD2
70R-12067MAD2 antibody

Popular Products