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HSP105 rabbit pAb

CAT: 0855-ES2580-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2580-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities., PTM:Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity., similarity:Belongs to the heat shock protein 70 family., subunit:Interacts with HSPA8/HSC70., tissue specificity:Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Description
Function: Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. PTM: Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity. similarity: Belongs to the heat shock protein 70 family. subunit: Interacts with HSPA8/HSC70. tissue specificity: Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.
Product Name Alternative
HSPH1; HSP105; HSP110; KIAA0201; Heat shock protein 105 kDa; Antigen NY-CO-25; Heat shock 110 kDa protein
UniProt
Q92598
Swiss Prot
Q92598
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human HSP105. AA range:791-840
Target
HSP105
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
100kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
100kD
Fragment
IgG
Subcellular Location
Cytoplasm .
Other Product Names
HSPH1; HSP105; HSP110; KIAA0201; Heat shock protein 105 kDa; Antigen NY-CO-25; Heat shock 110 kDa protein
Gene ID (Human)
10808

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