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GRK 5 rabbit pAb

CAT: 0855-ES2480-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2480-01Size:50 µL
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Background
This gene encodes a member of the guanine nucleotide-binding protein (G protein) -coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs) . [provided by RefSeq, Jul 2008]
Description
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). [provided by RefSeq, Jul 2008],
UniProt
P34947
Swiss Prot
P34947
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human GRK5. AA range:351-400
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
68kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
68kD
Fragment
IgG
Subcellular Location
Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Predominantly localized at the plasma membrane; targeted to the cell surface through the interaction with phospholipids. Nucleus localization is regulated in a GPCR and Ca (2+) /calmodulin-dependent fashion.
Other Product Names
GRK5; GPRK5; G protein-coupled receptor kinase 5; G protein-coupled receptor kinase GRK5
Gene ID (Human)
2869

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