GRK 3 rabbit pAb

• Background :

  The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008]

• Description :

  The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function. [provided by RefSeq, Jul 2008],

• UniProt :

  P35626

• Swiss Prot :

  P35626

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human GRK3. AA range:361-410

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight :

  80kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  80kD

• Fragment :

  IgG

• Subcellular Location :

  Cell junction, synapse, postsynapse . Cell junction, synapse, presynapse .

• Other Product Names :

  ADRBK2; BARK2; GRK3; Beta-adrenergic receptor kinase 2; Beta-ARK-2; G-protein-coupled receptor kinase 3

• Gene ID (Human) :

  157