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GRASP55 rabbit pAb

CAT: 0855-ES2471-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES2471-01Size:50 µL
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Background
This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Description
This gene encodes a member of the Golgi reassembly stacking protein family. These proteins may play a role in the stacking of Golgi cisternae and Golgi ribbon formation, as well as Golgi fragmentation during apoptosis or mitosis. The encoded protein also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone. A pseudogene of this gene is located on the short arm of chromosome 2. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],
UniProt
Q9H8Y8
Swiss Prot
Q9H8Y8
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human GORASP2. AA range:181-230
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
47kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
47kD
Fragment
IgG
Subcellular Location
Golgi apparatus membrane ; Lipid-anchor . Endoplasmic reticulum membrane . Golgi apparatus . Detected in the intermediate Golgi, membrane-associated (By similarity) . ER stress triggers its relocalization from Golgi to ER membrane (PubMed:27062250, PubMed:28067262) . .
Other Product Names
GORASP2; GOLPH6; Golgi reassembly-stacking protein 2; GRS2; Golgi phosphoprotein 6; GOLPH6; Golgi reassembly-stacking protein of 55 kDa; GRASP55; p59
Gene ID (Human)
26003

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